In addition to the published clinical studies listed below, additional peer-reviewed studies on BCL6 will be published as available. Please check back as we update these references often.
Published Clinical Studies
May 2022
BCL6, a key oncogene, in the placenta, pre-eclampsia and endometriosis
Frank Louwen, Nina-Naomi Kreis, Andreas Ritter, Alexandra Friemel, Christine Solbach, and Juping Yuan
March 2022 PCRS
Retrospective analysis of the relative value of IVF failures on BCL6 results
Dan Angress
March 2022
Can We Accurately Diagnose Endometriosis without a Diagnostic Laparoscopy?
Camran Nezhat, MD; Shruti Agarwal, DO
December 2021
Reliability of 2D/3D transvaginal ultrasonographic (TVUS) features (MUSA) in diagnosing
histological proven Adenomyosis using BCL6 biomarker in cases of reproductive failure
Hosam Zaki FRCOG, Hani El Maghrabi MSc., Hosam El Attar,Mostafa El Khosht
December 2021
"Gain Fading” A new reliable 3D transvaginal ultrasonographic(TVUS) feature helps in
diagnosing histological proven Adenomyosis using BCL6 biomarker in cases of
reproductive failure
Hosam Zaki FRCOG, Hani El Maghrabi MSc., Hosam El Attar,Mostafa El Khosht
September 2021
Evaluation of BCL6 and SIRT1 as Non-Invasive Diagnostic Markers of Endometriosis
Alison M. Sansone, Brooke V. Hisrich, R. Brandt Young, William F. Abel, Zachary Bowens, Bailey B. Blair, Avery T. Funkhouser, David P. Schammel, Lisa J. Green, Bruce A. Lessey, and Anna V. Blenda
December 2020
Positive Predictive Value of Endometrial BCL6 Overexpression in Patients With Pathology-Confirmed Endometriosis
Anupama Rambhatla, M.D., Catarina Silva, M.D.,Atena Asiaii, M.D., Robert Roman, M.D., Kimsa Nguyen, B.S., Camran Nezhat, M.D.
September 2020
Does GNRH Down Regulation Amongst Women With Abnormal BCL6 and/orf BETA 3 Integrin Expression Improve Implantation Rates? An Interim Analysis.
Garth Kellogg Summers, DO, Stephanie Gustin, MD, Taylar Lynn Swartz, DO, MPH.
October 2019
Unexplained recurrent pregnancy loss and unexplained infertility: twins in disguise.
Chelsea W Fox, Ricardo F Savaris, Jae-Wook Jeong, Tae Hoon Kim, Paul B Miller, Creighton E Likes, David P Schammel, Steven L Young, Bruce A Lessey
April 2019
Clinical approach to recurrent implantation failure: evidence-based evaluation of the endometrium
Harvey J. Kliman, M.D., Ph.D.a and David Frankfurter, M.D.
January 2019
Medical or surgical treatment before embryo transfer improves outcomes in women with abnormal endometrial BCL6 expression.
Creighton E. Likes, Leah J. Cooper, Jessica Efird, David A. Forstein, Paul B. Miller, Ricardo Savaris, Bruce A. Lessey
Gynecol Obstet Invest. 1994;37(3):191-5
Infertility due to diseased pelvic peritoneum: laparoscopic treatment
Manhes H, Shulman A, Haag T, Canis M, Demontmarin JL.
December, 2017
Endometrial BCL6 testing for the prediction of in vitro fertilization outcomes.
Laura D. Almquist, M.D., Creighton E. Likes, M.D., Benjamin Stone, B.S., Kaitlin R. Brown, B.S., Ricardo Savaris, M.D., Ph.D., David A. Forstein, D.O., Paul B. Miller, M.D., Bruce A. Lessey, M.D., Ph.D.
Fertil Steril. 2011 Mar 1;95(3):1113-4. doi: 10.1016/j.fertnstert.2010.12.017
Increased diagnostic accuracy of laparoscopy in endometriosis using indigo carmine: a new technique.
Rauh-Hain JA, Laufer MR.
July 28, 2017
KRAS Activation and overexpression of SIRT1/BCL6 Contributes to the Pathogenesis of Endometriosis and Progesterone Resistance.
Jung-Yoon Yoo1,2, Tae Hoon Kim1, Asgerally T. Fazleabas1,3, Wilder A. Palomino4, Soo Hyun Ahn 5, Chandrakant Tayade5, David P. Schammel6, Steven L. Young7, Jae-Wook Jeong1,3 & Bruce A. Lessey8.
Fertil Steril. 2011 Sep;96(3):e145; author reply e146. doi: 10.1016/j.fertnstert.2011.06.02
Does complete laparoscopic excision of endometriosis in teenagers really occur?
Laufer MR, Missmer SA.
Fertsert 2017 Jul volume 108, Issue 1, Pages 19–27
Endometrial receptivity in the eutopic endometrium of women with endometriosis: it is affected, and let me show you why.
Lessey, Bruce A and Kim, J. Julie.
Semin Reprod Med. 2010 Jan;28(1):5-16. doi: 10.1055/s-0029-1242988
Progesterone function in human endometrium: clinical perspectives.
Young SL, Lessey BA.
Reprod Sci. 2016 Sep;23(9):1234-41
Endometrial BCL6 Overexpression in Eutopic endometrium of women with endometriosis.
Evans-Hoeker E, Lessey BA, Jeong JW, Savaris RF, Palomino WA, Yuan L, Schammel DP, Young SL.